The film centers on a special organization that trains top secret agent animals. They are equipped with superior gear including highly developed earphones, that permit the mammals to talk to humans. The team includes cockroaches, guinea pigs Darwin (Sam Rockwell) who is the head of the team, Blaster (Tracy Morgan) who is responsible for weapon transportation, Speckles (Nicolas Cage) and a fly Mooch (Dee Bradley Baker) who is in-charge of reconnaissance. Ben (Zach Galifinakis) commands an illegal penetration in the house of Leonard Saber, owner of Saberling Technology. He has been under investigation for the past ten years. But unfortunately the team gets trapped in a pet shop. Juarez and Blaster get themselves sold to a family and manage to return to the base. Speckles dodges by playing dead and is thrown in the garbage truck. When Juarez and Blaster come back to Ben, they find that a dishonored Intel has a critical computer purpose to hide the scheme. They all decide to plant a virus in the mainframe computer and successfully do so with the help of PDA. In the end, the guinea pigs are appraised and you too can watch G-Force video to bear witness to the same.